The MAPT gene encodes “microtubule-associated protein tau” which is expressed within the neurons in the brain. Mutations in the MAPT gene can exert several different effects on how this process functions. These differences in function can be unique to each specific mutation, but all result in the formation of aggregated tau inclusions, also known as tangles, which are theorized to drive neuronal loss and brain atrophy.
Learn MoreSpread awareness of FTD, of the importance of genetic testing, and of Tau/MAPT.
Advocate for MAPT-specific trials and access to other FTD gene-specific trials.
Find, and connect to, the growing global network of MAPT families and researchers.
In 2023, one of the founding families of Cure MAPT FTD was featured inarticle by award-winning journalist and New York Times-bestselling author, Robert Kolker.
Read the full storyListen to the NYT podcastNovember 18, 2024
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Upcoming
Cure MAPT FTD member Linde Jacobs will speak at the UCSF Memory and Aging Center Lecture Series in a discussion on genetic FTD. Attend in person at the Helen Diller Family Cancer Research Auditorium (HD-160), or click the link below to register on Zoom.
Are you interested in genetic testing? MAPT trials? Support and resources for FTD? Contact us and we'll get back to you quickly.
hello@curemaptftd.org