Frontotemporal Dementia (FTD) is the most common form of dementia for those under 60. Under-diagnosed and currently incurable, FTD can be caused by a mutated gene, including the MAPT gene. Cure MAPT FTD raises awareness of the MAPT genetic mutation causing FTD, assists a global network of MAPT families, and advocates for trials that will lead to a cure.
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The MAPT gene encodes “microtubule-associated protein tau” which is expressed within the neurons in the brain. Mutations in the MAPT gene can exert several different effects on how this process functions. These differences in function can be unique to each specific mutation, but all result in the formation of aggregated tau inclusions, also known as tangles, which are theorized to drive neuronal loss and brain atrophy.
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Spread awareness of FTD, of the importance of genetic testing, and of Tau/MAPT.
Advocate for MAPT-specific trials and access to other FTD gene-specific trials.
Find, and connect to, the growing global network of MAPT families and researchers.
In 2023, one of the founding families of Cure MAPT FTD was featured inarticle by award-winning journalist and New York Times-bestselling author, Robert Kolker.
Read the full storyListen to the NYT podcastFebruary 7, 2025
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Join us to learn about the latest advances in medicine related to MAPT FTD; hear our five-year strategic plan; and meet our growing community, to share our voices and support one another.
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Are you interested in genetic testing? MAPT trials? Support and resources for FTD? Contact us and we'll get back to you quickly.
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