We envision a future free of MAPT FTD

Frontotemporal Dementia (FTD) is the most common form of dementia for those under 60. Under-diagnosed and currently incurable, FTD can be caused by a mutated gene, including the MAPT gene. Cure MAPT FTD raises awareness of the MAPT genetic mutation causing FTD, assists a global network of MAPT families, and advocates for trials that will lead to a cure.

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What is MAPT?

The MAPT gene encodes “microtubule-associated protein tau” which is expressed within the neurons in the brain. Mutations in the MAPT gene can exert several different effects on how this process functions. These differences in function can be unique to each specific mutation, but all result in the formation of aggregated tau inclusions, also known as tangles, which are theorized to drive neuronal loss and brain atrophy.

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Who we represent

We are a global community of families who have been impacted by MAPT FTD, often spanning multiple generations. Our group includes both individuals already diagnosed with FTD, positive MAPT carriers, and untested at 50% risk of carrying the genetic mutation.
Are you a foundation or donor who would like to support our efforts to create MAPT specific trials or gain entry into FTD/ALZ trials that have a TAU connection? 
Does someone you love have the MAPT gene and you're looking for support and answers?
Have you or a loved one just been diagnosed with FTD and are looking for genetic counseling to discover if there is a genetic-component?
If the answer to any of these questions is yes, you're in the right place.

Our Mission

Awareness

Spread awareness of FTD, of the importance of genetic testing, and of Tau/MAPT.

Advocacy

Advocate for MAPT-specific trials and access to other FTD gene-specific trials.

Connection

Find, and connect to, the growing global network of MAPT families and researchers.

In the News

The Vanishing Family

In 2023, one of the founding families of Cure MAPT FTD was featured inarticle by award-winning journalist and New York Times-bestselling author, Robert Kolker.

Read the full storyListen to the NYT podcast

Featured Event

November 18, 2024

1:00 pm

EST

Genetic FTD: Fighting for a Future

Upcoming

Featuring guest speaker

Linde Jacobs, RN

Cure MAPT FTD member Linde Jacobs will speak at the UCSF Memory and Aging Center Lecture Series in a discussion on genetic FTD. Attend in person at the Helen Diller Family Cancer Research Auditorium (HD-160), or click the link below to register on Zoom.

hosted by
UCSF

Our Stories

Linde's Story
Ansel's Story
Susan's Story

Our Sponsors

Looking to sponsor us?

Send us an email and we'll get back to you shortly

hello@curemaptftd.org

We want to hear from you!

Are you interested in genetic testing? MAPT trials? Support and resources for FTD? Contact us and we'll get back to you quickly.  

hello@curemaptftd.org

Want to hear from us?

We're on the front lines of fighting MAPT FTD. Want to keep up-to-date with what's going on in the efforts to cure MAPT FTD? Sign up for our news and monthly newsletter.